Western powers and Iran ended high-stakes talks in Geneva with an agreement to meet again.  We speak with Reza Aslan, author of "How to win a Cosmic War: God, Globalization, and the End of the War on Terror,” and contributing editor at The Daily Beast.

Time Inc. has just kicked off a year long project it's calling "Assignment Detroit." Time believes the city, the birthplace of the industrial age and the middle class, but where unemployment hovers today at 29%, is a window into the challenges facing modern America. So the media conglomerate has bought a house in Detroit and is filling it with journalists, photographers, videographers and bloggers from Time, Fortune, Money and Sports Illustrated magazines to document the city's peril and promise. Our guest is Dan Okrent, a Detroit native and former editor and writer for Time magazine.

The US Department of Energy is offering companies $10 million to invent a better light bulb. The device would have to use LED (light emitting diode) technology and produce the same quality light as Thomas Edison's incandescent bulb, but use 85% less energy and last 25 times longer. Jim Brodrick of DOE's Solid-State Lighting Program is our guest.

Would you be relieved or upset if you found out, through a genetic test that you can take at home, that you're at increased risk for Alzheimer's disease? Dr. Robert Green has studied the issue, and concludes that people can tolerate the bad news quite well. The problem is that people can easily misunderstand the results of home genetic tests, and there are also privacy concerns. Dr. Green is a professor of neurology and epidemiology at Boston University and a genetics resident at Harvard Medical School.

We take a few minutes to hear from listeners.

We hear from listeners; and Here and Now's Andrea Shea has the story of Ann Hobson-Pilot, who is retiring this season from the Boston Symphony Orchestra. Hobson-Pilot was the first African American woman to win a seat with the BSO.