The race for the late Senator Edward Kennedy's seat is down to the wire and the polls show the race is very close. Democrat Martha Coakley and Republican Scott Brown are trading ads and trying to raise a lot of money ahead of Tuesday's election. Some local radio stations have also been giving a lot of airtime to Brown's candidacy. We'll speak with Here and Now's Monica Brady Myerov. Independent candidate Joe Kennedy is also running.

Some doctors and patients are concerned that generic drugs for conditions like depression, heart conditions and epilepsy might not be as effective as the brand-name drugs. And insurers are encouraging more patients to take less-expensive generics. We speak with Lesley Alderman, who co-writes the "Patient Money" column for the New York Times.

In New York today, the United Nations is hosting a gathering of investors who represent $22 trillion in potential funds for the environment. At the Investor Summit on Climate Risk, they'll discuss climate change as a bottom line issue, and the clean energy sector as an economic opportunity. Investors, however, say governments have to get on board before they'll take the plunge. We talk about the summit with Mindy Lubber, President of its co-sponsor, Ceres.

We hear from listeners.

Inspired by his childhood fascination for his grandfather's player piano, renowned jazz musician Pat Metheny wanted to create an orchestra that played like a player piano but with 21st century technology. The result is his "Orchestrion" which uses mallets as well as computers to play a collection of musical instruments. The BBC's Andrew Purcell brings us the story.

• Astor Piazzolla, “Libertango” (performed by Cory Pesaturo)
• Art Van Damme Quintet “Don’t be That Way”
• Richard Galliano “A French Touch”
• Guy Klucevsek, “Altered Landscapes: Part One”
• Pinata Protest “Rocket”