Nobel Prize winner Mary Brunkow on immune system research

Mary Brunkow was awarded the 2025 Nobel Prize in Physiology or Medicine, along with Fred Ramsdell and Shimon Sakaguchi, for their "groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body.”

Brunkow speaks with Here & Now's Scott Tong about her work, and identifying the FOXP3 gene and the role regulatory T cells play in preventing autoimmune disease. She is a senior program manager in the Hood Lab at the Institute for Systems Biology (ISB) in Seattle.