AdvertisementDrug Cocktails Fuel Massachusetts' Overdose CrisisDecember 08, 2015Martha BebingerfacebookEmailA "speedball" mix of heroin and cocaine has caused overdose deaths for decades. Today, high-risk blends may alternatively include heroin or opioid pain pills plus Klonopin, Clonidine, or Fentanyl. (Flickr RM/Getty Images)