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Am I Destined To Be This Size?16:57
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(Public domain/National Human Genome Research Institute)
(Public domain/National Human Genome Research Institute)
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You know better than to expect life to be fair. But still, it's enough to drive anyone crazy: Some people seem to be able to eat anything they want and never gain weight. Others of us — well, as Juna says, you ask yourself: Is it all just genetic? Am I just "big-boned"?

She and Eddie dig into weight destiny in episode six, beginning with the basics of nature versus nurture: About 50% of weight variation stems from genetics, according to Rooth Loos, a professor of public health at the Icahn School of Medicine. The other 50% depends on environment (including exercise and outside cues that encourage unhealthy eating.) Here's a sentence that nicely sums it all up: Genes load the gun, and environment pulls the trigger.

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Carey Goldberg Twitter Editor, CommonHealth
Carey Goldberg is the editor of WBUR's CommonHealth section.

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